What Are Exosomes Injections?

Are you interested in exosomes and how this intriguing cellular regenerative technique can help you? You’re not alone: as encouraging results have shown that exosome injections can improve erectile dysfunction (ED) issues, exosomes have become a hot topic Let’s take a deeper dive into exosomes, the procedure for ED, and the results.

What Do Exosomes Fix?

First, a little explanation. Exosomes are microscopic extracellular vesicles, considerably smaller than cells. They form in endosome pockets inside the cell. Stay with me, I know this sounds like a lot of gibberish.

An endosome is somewhat like a small pocket of air or bubble inside of the cell. Several microparticles, such as proteins, messenger-RNA, micro-RNA, and valuable lipids, combine inside the endosome ‘bubble’. They bond together and then are ejected out of the cell, becoming what’s known as an ‘exosome’.

Exosomes are how cells communicate with each other, as exosomes carry messages amongst themselves. Basically, the exosomes give marching orders to other cells and kick-start the body’s natural healing process. It was traditionally thought that this expulsion was a waste by-product of the cells.

Now we understand that exosomes are not waste: what messages are these exosomes carrying? Often, these messages are the body’s cells communicating to others that repairs need to take place. Sometimes the exosomes signal for more aid to their location if major regeneration is required. As we age, our body’s cells are not able to function as well as they once did, and this is where exosome injections come in to save the day.

What Is the Procedure?

Here at Revived Performance for Men, we use the reputable product ExoFlo, which was created by Direct Biologics for our exosome injections. The treatment is administered through a quick, simple and direct injection to the treatment area. While other treatments like Plasma Rich Platelet (PRP) therapy require a small amount of the patient’s own blood, with ExoFlo injections blood draw is not necessary.

ExoFlo is sourced from donated mesenchymal stem cells (MSC) obtained from human bone marrow. That means we’re using the same exosomes that the body develops naturally! Direct Biologics processes and produces ExoFlo under the most stringent standards. They operate under what is considered current Good Manufacturing Practice (cGMP). This is the FDA’s highest enforced standard.

We take patient health and safety seriously and only use the most trustworthy substances in our treatments. If you’d like to learn more, visit our ExoFlo page. If you’re ready to take control of your ED and want to book an appointment, feel free to call us at (720) 263-9344 or schedule a free appointment online. Your first consultation is on the house.

Is Exosome Therapy Safe?

Exosome therapy is somewhat new to the erectile dysfunction arena. So, naturally, due caution is warranted. There are many bad actors in this market and the FDA has issued reports on concerns related to exosome cases. When digging through all of this, it can be hard to know what information to trust, so we’re going to break it down below:

Who Produces Exosomes?

First off, exosomes are made and used in your body organically. As a natural part of your body, there have been no long-term negative side effects reported from this treatment.

Exosomes are not a synthetic or man-made chemical, they’re an important part of your body that contain things such as protein and DNA. Exosome therapies, such as the newly popular ExoFlo service, are completely organic and natural. The exosomes are sourced from human bone marrow mesenchymal stroma/stem cells.

Direct Biologics, the company that produces ExoFlo, is working in complete agreement with the FDA. They take their safety concerns very seriously and maintain “Current Good Manufacturing Practices” (CGMP), which is the most superior standard of processing and manufacturing controls.

What About FDA Approval?

Exosomes are very closely related to what the FDA refers to as HCT/Ps (Human Cellular or Tissue products). This means they are governed very similarly to HCT/Ps. For now, the FDA approves no products with exosomes just like there are no approved HCT/Ps. The FDA requires HCT/Ps to be registered and does not require prior FDA approval. As long as the products are meant for homologous use and are minimally manipulated, they are safe.

What does homologous use mean? Basically it’s using an HCT/P to heal or repair a patient in the same way the donor’s body would use the cells or tissue. Exosomes assist with cell communications in everyone. And since exosomes are naturally found in everyone’s body and are performing the same function for the recipient as the donor, it falls under ‘homologous use.’

Direct Biologics’ ExoFlo is a minimally manipulated tissue that has one single donor for each lot. ExoFlo contains no animal products, chemicals or drugs in the processing and isolation of the exosome products. Direct Biologics is actively seeking FDA approval and working hard to ensure a safe to use product.

In fact, Direct Biologics just recently received FDA approval to proceed with their second ExoFlo IND (Investigational New Drug) for post-acute COVID-19 syndrome and chronic post-COVID-19 syndrome last week. This is exciting and promising news for this amazing product.

You can rest assured that Revived Performance for Men has your safety in mind. Our Denver office follows a strict standard maintained by Sarah Kurts. Sarah is a Board Certified Physician Assistant and graduated with distinction from the University of Virginity. She earned her Physician Assistant degree from the University of Colorado Health Sciences Center.

If you’re interested in learning more about exosomes, feel free to check out our ExoFlo page. If you have any questions or you’re ready to fix your ED, please contact us at (720) 263-9344 or schedule a free consultation online.

How Do Exosomes Work?

For a long time, microscopic entities known as Exosomes were overlooked as nothing more than scrap waste. However, over time, new discoveries have shown how vital they are to repairing damaged tissue.

Where Do They Come From?

Exosomes are one of two types of cells known as extracellular vesicles, the other being microparticles. They are only a couple nanometers in size. Extracellular vesicles can come from different parts of the cell. Inside of a cell, a part of the membrane wall forms inward. This creates a special form of lipid vesicle called an endosome. In layman’s terms, the endosome is like a small pocket or bubble inside of the cell. 

Proteins, microRNA, and messenger RNA become enclosed within the endosome ‘pocket’ membrane. These proteins and RNA are now trapped together inside the endosome. Trapped inside the ‘pocket’, they become an extracellular vesicle. 

In order for the newly created extracellular vesicle to now get out of the endosome and the cell, the endosome has to fuse with the surface of the cell. This releases the extracellular vesicle out of the cell. 

Think of it like pulling your pocket inside out to get rid of lint. Except, exosomes are way more powerful than lint.

What Do Exosomes Do?

Extracellular vesicles used to be regarded as merely being leftover waste of the cells. However, when researchers looked at these microscopic bits more they realized something incredible. These extracellular vesicles were actually a clever method of passing messages back and forth between cells. 

Because of their small size, exosomes  are able to pass between cell membranes. They act as mail carriers delivering instructions and information between cells. When the raw building materials of the body, known as stem and progenitor cells, don’t know what to do, exosomes step in to guide them. 

These signals also request the body to send more stem cells to the area, organizing an effective and well-regulated process of healing. 

ExoFlo, the leading product in exosome therapy, is made by Direct Biologics. They’re certified by the FDA’s regulations on Current Good Manufacturing Practice. Each cc of ExoFlo contains over 10 Billion exosomes. For more information, we have an extensive amount of details on this ExoFlo page
If you’d like to learn more about ExoFlo and which treatment would best fit your individual situation, please book an appointment or call our direct line (720) 263-9344. We look forward to hearing from you!

What is Exosome Therapy?

Scientists can’t help but get excited and overcomplicate exosome therapy. Granted, exosomes are very complex, but scientists tend to add needless complexity when discussing the topic. As we explain this amazing regenerative medicine, we want to keep it simple and understandable. 

What Are Exosomes?

First off, a quick summary of what these little guys are. Exosomes simply help cells talk to each other and give the body instructions to start repairing itself. Kind of like a foreman or supervisor, exosomes oversee the performance of the body’s natural stem cells. They manage these cells and direct them on how to heal, repair, and restore damaged tissues. 

Exosomes are one of two types of extracellular vesicles. ExoFlo’s exosomes are about 30-150 nanometers. They carry RNAs, proteins and lipids from their parent cells. It was thought that extracellular vesicles were a waste by-product of cells until it was investigated more. Researchers discovered that these tiny organisms are what actually allows communication between cells.

How Can Exosomes Help?

Stem cells are the body’s raw materials and their descendants are progenitor cells. Both work to restore, heal, and repair the body’s damaged tissues. However, sometimes there is a flaw that stops these cells from doing their job. This is where ExoFlo exosomes come in to save the day. 

ExoFlo exosomes get these faulty stem cells back to working order. They also signal to the body to send more stem cell building material to the damaged area for repair. This promotes an organized and effective healing process. 

As mentioned, exosomes are natural to the body. ExoFlo comes from human bone marrow mesenchymal stem/stromal cells (MSC). The proteins and RNA naturally found in MSC from bone marrow have a special property. 

Typically when the body tries to heal itself, it often involves inflammation. Obviously, this can be an obstacle. However, bone marrow MSC has been shown to control this inflammatory restoration process. It fine-tunes the proper response of inflammation to allow for optimal healing. 

Why ExoFlo?

I know what you’re thinking: If they’re naturally in the body, why can’t the body just fix itself on its own? Why do you need ExoFlo?

As great as our bodies are, they aren’t perfect, which is where ExoFlo comes in. An ExoFlo injection is able to speed up the body’s healing process by pin-pointing the problem and delivering the exosomes where they need to go immediately.

Direct Biologics, maker of ExoFlo, is certified by the FDA as a Current Good Manufacturing Practice company and they are a leading innovator of regenerative medical products. The company’s primary focus is optimizing the potential of regenerative technologies. 

To that end, each vial of ExoFlo is processed for purity in a sterile filtered facility. Every cc of ExoFlo contains over 10 Billion extracellular vesicles. You can rest assured in ExoFlo’s performance.

What’s The Procedure?

The excellent thing about ExoFlo is how easy it is. You don’t have to think about it or remember to take any pills. After the treatment, the exosomes go to work on their own. Additionally, the procedure itself is a simple injection.

Where Can I Learn More?

The video below explains about ExoFlo exosome therapy. If you would like additional information on ExoFlo, you can contact us directly or visit our informational page.

How To Get Started

Our Board Certified Physician Assistant Sarah Kurts will help you along the process. Schedule an appointment online or give us a call at (720) 263-9344.